Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NFE2L1 All Species: 14.24
Human Site: S379 Identified Species: 31.33
UniProt: Q14494 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14494 NP_003195.1 772 84704 S379 S Q D F L L F S P E V E S L P
Chimpanzee Pan troglodytes XP_001173196 742 81481 P356 S P E V E S L P V A S S S T L
Rhesus Macaque Macaca mulatta XP_001087083 772 84726 S379 S Q D F L L F S P E V E S L P
Dog Lupus familis XP_851865 781 85498 S380 S Q D F S L F S P E A E S L P
Cat Felis silvestris
Mouse Mus musculus Q61985 741 81527 L356 F S P E V E S L P V A S S S T
Rat Rattus norvegicus O54968 604 67684 S255 H G F E D S F S S I L S T D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513064 403 43791 P54 N L T G L F L P A P L N G S A
Chicken Gallus gallus Q5ZL67 772 85168 S381 S Q D F S L F S S E I E S P S
Frog Xenopus laevis NP_001080013 718 79943 S359 S P V P Q L S S H N S T D L N
Zebra Danio Brachydanio rerio XP_001920265 797 88024 C398 Q Q A L L P S C G Q D F P T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P20482 1383 147394 N892 N P H G N Q A N G A S G G V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 96.1 99.7 96 N.A. 93.1 27.7 N.A. 40.6 83.8 62.1 59 N.A. 23.5 N.A. N.A. N.A.
Protein Similarity: 100 96.1 100 97.3 N.A. 94.6 44.4 N.A. 45.8 90.5 74.2 73.9 N.A. 34.2 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 86.6 N.A. 13.3 13.3 N.A. 6.6 66.6 26.6 13.3 N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 20 100 86.6 N.A. 20 26.6 N.A. 20 73.3 26.6 20 N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 10 0 0 0 10 0 10 19 19 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 37 0 10 0 0 0 0 0 10 0 10 10 10 % D
% Glu: 0 0 10 19 10 10 0 0 0 37 0 37 0 0 0 % E
% Phe: 10 0 10 37 0 10 46 0 0 0 0 10 0 0 0 % F
% Gly: 0 10 0 19 0 0 0 0 19 0 0 10 19 0 10 % G
% His: 10 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 10 0 10 37 46 19 10 0 0 19 0 0 37 19 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 19 0 0 0 10 0 0 10 0 10 0 10 0 0 10 % N
% Pro: 0 28 10 10 0 10 0 19 37 10 0 0 10 10 28 % P
% Gln: 10 46 0 0 10 10 0 0 0 10 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 55 10 0 0 19 19 28 55 19 0 28 28 55 19 10 % S
% Thr: 0 0 10 0 0 0 0 0 0 0 0 10 10 19 10 % T
% Val: 0 0 10 10 10 0 0 0 10 10 19 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _